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Volume 12, Issue 1 (Winter 2026 2026)
Caspian J Neurol Sci 2026, 12(1): 51-61 |
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Ethics code: IR.GUMS.REC.1400.198
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Shokrgozar S, Gol Z, Soleimani R, Nejatifar F, Nazari Z, Zare R. Psychoeducational Intervention on Mental Adjustment in Gastrointestinal Cancer Patients: A Randomized Clinical Trial. Caspian J Neurol Sci 2026; 12 (1) :51-61
URL: http://cjns.gums.ac.ir/article-1-815-en.html
URL: http://cjns.gums.ac.ir/article-1-815-en.html
Somayeh Shokrgozar1 
, Zahra Gol *2 , Robabeh Soleimani1 , Fatemeh Nejatifar3 , Zahra Nazari4 , Roghayeh Zare5
, Zahra Gol *2 , Robabeh Soleimani1 , Fatemeh Nejatifar3 , Zahra Nazari4 , Roghayeh Zare5
1- Department of Psychiatry, Kavosh Cognitive Behavior Sciences and Addiction Research Center, Faculty of Medicine, Guilan University of Medical Sciences, Rasht, Iran
2- Department of Psychiatry, Kavosh Cognitive Behavior Sciences and Addiction Research Center, Faculty of Medicine, Guilan University of Medical Sciences, Rasht, Iran ,gol.ir1988@gmail.com
3- Department of Internal Medicine, Faculty of Medicine, Guilan University of Medical Sciences, Rasht, Iran
4- Department of Psychology, La.C., Islamic Azad University, Lahijan, Iran
5- Guilan Road Trauma Research Center, Trauma Institute, Guilan University of Medical Sciences, Rasht, Iran
2- Department of Psychiatry, Kavosh Cognitive Behavior Sciences and Addiction Research Center, Faculty of Medicine, Guilan University of Medical Sciences, Rasht, Iran ,
3- Department of Internal Medicine, Faculty of Medicine, Guilan University of Medical Sciences, Rasht, Iran
4- Department of Psychology, La.C., Islamic Azad University, Lahijan, Iran
5- Guilan Road Trauma Research Center, Trauma Institute, Guilan University of Medical Sciences, Rasht, Iran
Abstract: (11 Views)
Background: Patients with gastrointestinal (GI) cancers often experience psychological distress that impacts adjustment and quality of life (QoL). This study evaluated the effectiveness of a brief psychoeducational intervention in improving psychological outcomes in newly diagnosed GI cancer patients.
Materials & Methods: In this randomized clinical trial, 84 eligible patients out of 113 patients in a city in north of Iran in 2021 were assigned to either an intervention group (n=42) or a control group (n=42). The intervention group received four 45-minute psychoeducational sessions led by a psychiatry resident and a psychologist. The control group received standard care and was wait listed for the intervention. Psychological adjustment, anxiety and depression, and QoL were assessed before and after the intervention using the Persian versions of the mini-mental adjustment to cancer (Mini-MAC) scale, hospital anxiety and depression scale (HADS), and EORTC QLQ-C30, respectively. We used independent t-test, Mann–Whitney U test, chi-square /Fisher’s exact tests, and generalized estimating equation model to analyze the data using SPSS software, version 22.
Results: Sixty-eight participants completed the study. The intervention group showed significant improvements across all Mini-MAC subscales and reductions in anxiety (r=0.94, P<0.001) and depression (r=0.92, P<0.001). QoL scores improved significantly in several domains, including global health (r=0.92, P<0.001) and emotional functioning (r=0.94, P<0.0001).
Conclusion: The intervention enhanced psychological adjustment and well-being in GI cancer patients. Integrating brief psychoeducational support into oncology care may benefit patients, particularly in low-resource settings.
Materials & Methods: In this randomized clinical trial, 84 eligible patients out of 113 patients in a city in north of Iran in 2021 were assigned to either an intervention group (n=42) or a control group (n=42). The intervention group received four 45-minute psychoeducational sessions led by a psychiatry resident and a psychologist. The control group received standard care and was wait listed for the intervention. Psychological adjustment, anxiety and depression, and QoL were assessed before and after the intervention using the Persian versions of the mini-mental adjustment to cancer (Mini-MAC) scale, hospital anxiety and depression scale (HADS), and EORTC QLQ-C30, respectively. We used independent t-test, Mann–Whitney U test, chi-square /Fisher’s exact tests, and generalized estimating equation model to analyze the data using SPSS software, version 22.
Results: Sixty-eight participants completed the study. The intervention group showed significant improvements across all Mini-MAC subscales and reductions in anxiety (r=0.94, P<0.001) and depression (r=0.92, P<0.001). QoL scores improved significantly in several domains, including global health (r=0.92, P<0.001) and emotional functioning (r=0.94, P<0.0001).
Conclusion: The intervention enhanced psychological adjustment and well-being in GI cancer patients. Integrating brief psychoeducational support into oncology care may benefit patients, particularly in low-resource settings.
Keywords: Gastrointestinal (GI) neoplasms, Adaptation, Mental health, Anxiety, Depression, Quality of life (QoL)
Type of Study: Research |
Subject:
Special
Received: 2025/11/6 | Accepted: 2025/12/20 | Published: 2026/01/11
Received: 2025/11/6 | Accepted: 2025/12/20 | Published: 2026/01/11
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