Volume 8, Issue 4 (Autumn 2022)                   Caspian.J.Neurol.Sci 2022, 8(4): 252-267 | Back to browse issues page


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Nikbakht H, Shojaie L, Niknejad N, Hassanipour S, Soleimanpour H, Heidari S, et al . Mortality Rate of Acute Stroke in Iran: A Systematic Review and Meta-Analysis. Caspian.J.Neurol.Sci 2022; 8 (4) :252-267
URL: http://cjns.gums.ac.ir/article-1-568-en.html
1- Social Determinants of Health Research Center of Babol University of Medical Sciences, Babol University of Medical Sciences, Babol, Iran
2- Department of Medicine, Keck School of Medicine, University of Southern California, Los Angeles, United States
3- Department of Population and Public Health, School of Population and Public Health, The University of British Columbia, Vancouver, Canada
4- Department of Cardiology, Cardiovascular Diseases Research Center, School of Medicine, Heshmat Hospital, Guilan University of Medical Sciences, Rasht, Iran
5- Aging Research Institute, Tabriz University of Medical Sciences, Tabriz, Iran
6- Nursing School of Miyandoab, Urmia University of Medical Sciences, Urmia, Iran
7- Student Research Committee, Shiraz University of Medical Sciences, Shiraz, Iran
8- Student Research Committee, Road Traffic Injury Research Center, Tabriz University of Medical Sciences, Tabriz, Iran
Abstract:   (310 Views)
Background: There is limited data about the short-term stroke mortality rates for patients in treatment
settings.
Objectives: This study aimed to estimate the short-term stroke (in hospital, one month, one year)
mortality rates in Iran through a systematic review and meta-analysis.
Materials & Methods: We searched electronic databases, including three national (IranDoc, Megiran,
SID) and four international (Scopus, PubMed, Web of Science, Google Scholar), from January 1990
to March 2020. We considered all observational studies on stroke mortality, such as cohort and crosssectional
studies. Furthermore, the sub-group analyses were performed based on each province and metaregression
analysis based on the study’s year and patients’ mean age.
Results: Among 143 studies, 28 were eligible (11 cohort and 17 cross-sectional studies). Based on
the random model, the mortality rates for in-hospital, 1-month, and 1-year mortality were reported as
18.71% (95% CI: 15.09%-22.34%), 23.43% (95% CI: 20.08%-26.78%), and 34.44% (95% CI: 32.02%-
36.85%), respectively. The results also revealed that mortality rates were neither related to the year studies
conducted nor to the patient’s age.
Conclusion: Approximately one-fifth of stroke patients in Iran die in the hospital after admission. The
mortality rate increased in the one-month and one-year period, and about one-third of the patients died
in the first year. Therefore, it is cardinal to focus on programs and solutions in which we can ameliorate
mortality in the short-term period after stroke by performing primary specific treatments on patients.
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Type of Study: Review | Subject: Special
Received: 2022/09/14 | Accepted: 2022/09/28 | Published: 2022/09/28

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