شنبه 29 اردیبهشت 1403
دوره 9، شماره 2 - ( 1-1402 )
جلد 9 شماره 2 صفحات 101-92 |
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Maleknejad S, Farzi F, Heidarzadeh A, Safaei Asl A, Hasanzadeh Rad A, Hoseini Nouri S A. Oral Ketamine or Nasal Midazolam for Sedation in Pediatric Upper Gastrointestinal Endoscopy. Caspian J Neurol Sci 2023; 9 (2) :92-101
URL: http://cjns.gums.ac.ir/article-1-618-fa.html
URL: http://cjns.gums.ac.ir/article-1-618-fa.html
Oral Ketamine or Nasal Midazolam for Sedation in Pediatric Upper Gastrointestinal Endoscopy. مجله علوم اعصاب کاسپین. 1402; 9 (2) :92-101
چکیده: (497 مشاهده)
Background: There is no agreement on the route of administration and the drug of choice for providing adequate sedation for pediatric invasive procedures.
Objectives: We compared the utility, safety, and sedation effects of intranasal midazolam and oral ketamine.
Materials & Methods: This double-blind clinical trial was performed on 100 children aged 2 to 14 years who were candidates for upper gastrointestinal (GI) endoscopy. Patients were randomly assigned to two groups: ketamine (4 mg/kg orally) and midazolam (0.1 mg/ kg intranasal). Sedation score, fear levels, children’s behavior at the time of separation from parents, and vital signs were recorded.
Results: Higher systolic blood pressure was seen in children who received ketamine (P=0.012) and lower arterial oxygen saturation in the midazolam group (P=0.023). Also, the level of sedation showed no significant difference between the groups.
Conclusion: Based on the results, administering oral ketamine or intranasal midazolam before endoscopy induced a similar sedation score in children. Also, both methods could be safe and non-invasive modalities for sedation.
Objectives: We compared the utility, safety, and sedation effects of intranasal midazolam and oral ketamine.
Materials & Methods: This double-blind clinical trial was performed on 100 children aged 2 to 14 years who were candidates for upper gastrointestinal (GI) endoscopy. Patients were randomly assigned to two groups: ketamine (4 mg/kg orally) and midazolam (0.1 mg/ kg intranasal). Sedation score, fear levels, children’s behavior at the time of separation from parents, and vital signs were recorded.
Results: Higher systolic blood pressure was seen in children who received ketamine (P=0.012) and lower arterial oxygen saturation in the midazolam group (P=0.023). Also, the level of sedation showed no significant difference between the groups.
Conclusion: Based on the results, administering oral ketamine or intranasal midazolam before endoscopy induced a similar sedation score in children. Also, both methods could be safe and non-invasive modalities for sedation.
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