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Farjoud Kouhanjani M, Haghighat S, Poursadeghfard M. Multiple Sclerosis Diagnosed in a Woman With Von-Willebrand Disease: A Case Report. Caspian J Neurol Sci 2022; 8 (3) :188-191
URL: http://cjns.gums.ac.ir/article-1-550-fa.html

Background: Von-Willebrand Disease (VWD) is the most common inherited bleeding disorder with an autosomal inheritance pattern. Multiple Sclerosis (MS) is a neurological disease, causing neurodegeneration and demyelination of the central nervous system through autoimmune mechanisms, and is a major cause of non-traumatic disabilities in youths. Some studies have shown the higher plasma activity of Von-Willebrand Factor in the active phase of MS. However, we could not find any study reporting co-occurrence of VWD and MS.
Case Presentation and Intervention: In this case report, we present a woman with VWD who had optic neuritis 8 years ago and a new onset right-side hemiparesis. She was finally diagnosed as a new case of MS.
Conclusion: There is a case of both VWD and MS; however, further investigation is needed regarding the association of VWD and MS.