Caspian Journal of Neurological Sciences
مجله علوم اعصاب کاسپین
Caspian J Neurol Sci
Literature & Humanities
http://cjns.gums.ac.ir
1
admin
2383-4307
2423-4818
10.32596
en
jalali
1397
1
1
gregorian
2018
4
1
4
2
online
1
fulltext
en
Prevalence of Tremors in Patients With Multiple Sclerosis: A Cross-Sectional Study in Isfahan, Iran
تخصصي
Special
كاربردي
Applicable
<div style="text-align: justify;"><strong>Background:</strong> Multiple Sclerosis (MS) is a demyelinating disorder of the central nervous system. Tremors are a common problem in the patients suffering from MS which is mostly observed in the arms but can also affect the other body parts. There have been few studies on tremors among the MS patients. <br>
Objectives: This study is the first to report the prevalence of tremor in a group of MS patients in Iran. We have also reported the possible associations between the presence of tremor and different forms of ataxia. <br>
<strong>Materials & Methods:</strong> This study was performed on a group of MS patients in Alzahra hospital, Isfahan, Iran. Patients were interviewed, and a neurologist carried out the neurological examinations, including the evaluation of the type of tremor with the help of Expanded Disability Status Scale (EDSS); ataxia clinical scale for dysmetria, dysdiadochokinesia, dysarthria and gait ataxia. Movement Disorder Society-Unified Parkinson’s Disease Rating Scale (MDS-UPDRS) part 3.15 to 3.17 was also used for tremor classification. Tremor-related disability and handicap were scored by using Disability and Handicap Questionnaires. <br>
<strong>Results:</strong> Out of the 164 patients, 113 had tremor (69%) of which 23 were males (20%), and 90 were females (80%). A strong correlation between tremor and ataxia was reported while there were no correlations between tremor and patient’s gender, type of MS or the first clinical presentation. Twenty-three of the 164 patients suffered from the incapacitating tremor and had serious problems doing certain tasks. We also reported tremor to greatly affect the daily activities.<br>
<strong>Conclusion:</strong> The frequency of tremor in MS is relatively high. Strong correlation is between tremor and ataxia but not with the gender, the type of MS or the first clinical presentation. The tremor of MS greatly affected the activities of the daily living.</div>
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Multiple Sclerosis, Tremor, Prevalence
71
76
http://cjns.gums.ac.ir/browse.php?a_code=A-10-142-1&slc_lang=en&sid=1
Mehri
Salari
mehri.salari@gmail.com
0000-00021675-681X
No
Department of Neurology, Shahid Beheshti University of Medical Sciences, Tehran, Iran
Omid
Mirmosayyeb
omid.mirmosayyeb@gmail.com
0000-0002-3756-2985
No
Isfahan Neuroscience Research Center, Department of Neurology, Alzahra Hospital, Isfahan University of Medical Sciences, Isfahan, Iran
Masoud
Etemadifar
etemadifar.1963@gmail.com
0000-0002-0066-3782
No
Department of Neurology, Isfahan University of Medical Sciences, Isfahan, Iran
Hamidreza
Hatamian
No
Department of Neurology, Poursina Hospital, School of Medicine, Guilan University of Medical Sciences, Rasht, Iran
Zohre
Rahimi
fasa775@yahoo.com
0000-0003-4742-4102
No
Isfahan Neuroscience Research Center, Department of Neurology, Alzahra Hospital, Isfahan University of Medical Sciences, Isfahan, Iran
Hosein
Delavar Kasmaei
h.dk59@yahoo.com
0000-0002-8689-9058
No
Department of Neurology, Shohadaye Tajrish Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran
Sare
Shahidi
fasa775.fs@gmail.com
0000-0002-5378-5708
No
Isfahan Neuroscience Research Center, Department of Neurology, Alzahra Hospital, Isfahan University of Medical Sciences, Isfahan, Iran
Fateme
Sabeti
sabetifateme@yahoo.com
0000-0001-7372-2328
Yes
School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran