• Early life interferences influence postnatal brain development.
• Morphine consumption during the lactation period induces the morphine dependence of rat offspring.
• Morphine consumption during the lactation period decreases synaptic plasticity in rat offspring.

• The test-retest reliability of the Persian Version Mindful Eating Questionnaire (P-MEQ) was acceptable to good.
• The deleting of 4 items (4, 8, 14, and 25) due to obtaining the weak factor loading could improve the values of fit
indices.
• Internal consistency and stability over time of the P-MEQ score were acceptable.
• The first and second-order five-factor structural model of P-MEQ has a good fit in the Iranian population.

• Photobiomodulation showed short-term and long-term analgesic effects in patients with adhesive capsulitis.
• Compared with routine physical therapy, photobiomodulation did not reveal significant changes in the range of motion
and muscle thickness and function in patients with adhesive capsulitis.

• The most commonly used disease-modifying therapy among MS patients is Rituximab.
• Disease-modifying therapies did not have adverse outcomes during Coronavirus Disease 2019 (COVID-19) pandemic.
• The mortality rate of MS patients is not higher than the general population.

• The prevalence and average annual incidence among the patients were 57.77 and 4.35 per 100000 individuals from
2006 to 2019, respectively, in Khuzestan Province.
• The MS incidence increased slightly from 5.01 to 4.87 per 100000 subjects from 2006 to 2019 in
Khuzestan Province.
• The increase of MS incidence from 2006 to 2019 has been higher for women than men.
• The relevant results indicated that Khuzestan Province is a high-risk area for MS, and the prevalence and incidence
of the disease are increasing.

• The autoimmune nature of the NMOSD disease leads to the use of immunosuppressive therapy, like anti-CD20
drugs, in its treatment. Using immunosuppressive drugs potentially makes patients more susceptible to infections.
• This survey showed that despite immunosuppressive therapy in NMOSD patients, the cases infected by COVID-19
experienced no severe complications or atypical presentation.
• The NMOSD annual relapse rate did not increase during the COVID-19 pandemic.
• We suggested that immunosuppressant therapy be continued routinely in NMOSD patients during the COVID-19
epidemic. Still, any expansion of dosing interval should be according to the clinical and paraclinical findings of patients
under the neurologist’s recommendation.

α-Pinene is one of the main constituents of plant extracts.
● Along with exercise, α-pinene can have preventive effects in pentylenetetrazole-induced seizures in mature male rats

● Patients with Multiple Sclerosis (MS) and epilepsy experienced depression, anxiety, stress, fear, poor sleep quality, mental fatigue, and poor quality of life during the Coronavirus Disease 2019 (COVID-19) pandemic.
● Quarantine has limited patients’ access to medication and treatment, resulting in increased seizure attacks and disease severity.
● Factors such as female gender, loneliness, economic problems, the lack of social support, old age, and the lack of exercise also affected the severity of depressive symptoms, stress, and anxiety in patients with MS and epilepsy during the COVID-19 pandemic.