دوره 8، شماره 4 - ( 6-1401 )                   جلد 8 شماره 4 صفحات 251-244 | برگشت به فهرست نسخه ها


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چکیده:   (958 مشاهده)
Hippocampus is a part of the brain that has an essential role in memory and learning. It is involved
in many cognitive and behavioral phenomena, including the pattern separation process: the ability
to distinguish patterns with very high similarity. The present study compared the models of pattern
separation in the dentate gyrus of the hippocampus and aimed to investigate the significant cells
and factors affecting pattern separation. In this review, we intend to describe the anatomy of the
dentate gyrus as a part of the hippocampus, which has an essential role in pattern separation. Other
adjacent neural populations are further addressed, too. Models of the dentate gyrus, including
neurocomputation and functional, that represent the process of separating patterns in the dentate
gyrus are reviewed and analyzed. In this regard, five major models were highlighted and compared
from several perspectives. While some models are based on the entorhinal cortex and dentate gyrus
regions, others point to the mediation of cornu ammonis (CA3) as well. Models with the lowest
cells for pattern separation are addressed first. Finally, inhibition is discussed in the comparison of
pattern separation models.
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نوع مطالعه: مروری | موضوع مقاله: تخصصي
دریافت: 1401/6/23 | پذیرش: 1401/7/6 | انتشار: 1401/7/6

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