Caspian Journal of Neurological Sciences
مجله علوم اعصاب کاسپین
Caspian J Neurol Sci
Literature & Humanities
http://cjns.gums.ac.ir
1
admin
2383-4307
2423-4818
10.32596
en
jalali
1399
4
1
gregorian
2020
7
1
6
3
online
1
fulltext
en
The Effect of Amino Acid, Carbohydrate, and Lipid Metabolism Disorders on Eyes
تخصصي
Special
مروری
Review
Inherited metabolic disorders (IMDs) are a class of genetic disorders. Each metabolic disorder may have different forms with different age of onset, clinical manifestations, severity, and even type of inheritance. Ideally, a group of different specialists, including ophthalmologists, pediatricians, biochemists, and medical geneticists are needed for the final diagnosis and management of IMDs. Because of the importance of the aforementioned issue, we investigated the effect of IMDs on the eye in this review. Metabolic disorders can induce abnormalities in conjunctiva, cornea, lens, retina, optic nerve, and eye motility. In this study, the authors aimed to address the effect of metabolic diseases of amino acids, carbohydrates, and lipids on eye metabolism. Because of the direct toxic mechanisms of abnormal metabolites on the eyes and regarding the effect of eye monitoring on follow-up, management, and treatment of IMDs, a detailed ophthalmological assessment is essential.
Metabolic diseases, Congenital, Eye
190
196
http://cjns.gums.ac.ir/browse.php?a_code=A-10-32-106&slc_lang=en&sid=1
Abdolreza
Medghalchi
0000-0002-5007-859X
No
Eye Research Center, Guilan University of Medical Sciences, Rasht, Iran
Afagh
Hassanzadeh Rad
0000-0001-6980-8866
No
Pediatric Diseases Research Center, Guilan University of Medical Sciences, Rasht, Iran
Reza
Soltani-Moghadam
0000-0001-9661-3036
No
Eye Research Center, Guilan University of Medical Sciences, Rasht, Iran
Setila
Dalili
0000-0001-9591-0821
Yes
Pediatric Diseases Research Center, Guilan University of Medical Sciences, Rasht, Iran