Caspian Journal of Neurological Sciences
مجله علوم اعصاب کاسپین
Caspian J Neurol Sci
Literature & Humanities
http://cjns.gums.ac.ir
1
admin
2383-4307
2423-4818
10.32596
en
jalali
1398
4
1
gregorian
2019
7
1
5
3
online
1
fulltext
en
Contrast Induced Nephropathy After Brain and Cervical CT Angiography in Stroke Patients: A Prospective Study
تخصصي
Special
پژوهشي
Research
<div style="text-align: justify;"><strong>Background</strong>: Contrast-induced nephropathy (CIN) is a major side effect of intravenous iodinated contrast and causes both short- and long-term adverse effects. While diagnostic and interventional procedures of brain ischemia are recently advanced, it is necessary to be cautious about its major side effect.<br>
<strong>Objectives</strong>: To evaluate CIN and its risk factors in neurology patients after brain and cervical CT angiography. <br>
<strong>Materials & Methods</strong>: This prospective cross-sectional study was conducted on all patients who were admitted in stroke department of Nemazee hospital, affiliated to Shiraz University of Medical Sciences, Fars, Iran, and had undergone brain and cervical CT angiography from September 2014 to September 2016. Blood urea nitrogen (BUN) and creatinine (Cr) before contrast (BUN1, Cr1), 3 days after contrast (BUN2, Cr2), and 30 days after contrast (BUN3, Cr3) were recorded. t-test, paired t-test, Chi-squared test, repeated measurement-test and also SPSS V. 21 are used for statistical analysis.<br>
<strong>Results</strong>: 5(2.7%) patients developed CIN after receiving contrast. However, repeated measurement of glomerular filtration rate (GFR) and Cr at the end of one month showed no significant changes between Cr3 and GFR3 in 2 groups of non-CIN and CIN patients, and all patients showed normal renal function at that time. Multiivariate logistic regression analysis demonstrated that hemoglobin (Hb) level is related to CIN (OR:0.5, CI: 0.28-0.90). <br>
<strong>Conclusion</strong>: Our data showed that the rate of CIN in neurovascular evaluation was insignificant, but it is related to Hb level.</div>
Computed Tomography Angiography, Stroke, Kidney
140
146
http://cjns.gums.ac.ir/browse.php?a_code=A-10-200-2&slc_lang=en&sid=1
Maryam
Poursadeghfard
poursadra@gmail.com
0000-0003-2375-6014
Yes
Clinical Neurology Research Center, Shiraz University of Medical Sciences, Shiraz, Iran
Amir
Torkaman
amirtkn2015@gmail.com
0000-0003-2375-6014
No
Clinical Neurology Research Center, Shiraz University of Medical Sciences, Shiraz, Iran
Mahshad
Moazzam
mahshad.mzzm@gmail.com
0000-0003-2375-6014
No
school of medicine, Kazeroon Branch, Islamic Azad University, Kazeroon, Iran
Aida
Aramesh
aidaaramesh@gmail.com
0000-0003-2375-6014
No
school of medicine, Kazeroon Branch, Islamic Azad University, Kazeroon, Iran
Mojtaba
Neydavoodi
0000-0001-8099-9966
No
Clinical Neurology Research Center, Shiraz University of Medical Sciences, Shiraz, Iran