@ARTICLE{Shaygannejad, author = {Manouchehri, Navid and Nehzat, Nasim and Mirmosayeb, Omid and Shaygannejad, Vahid and Barzegar, Mahdi and }, title = {Tumefactive Brain Lesions in Patients with Neuromyelitis Optica Spectrum Disorder}, volume = {5}, number = {2}, abstract ={Background: Neuromyelitis Optica Spectrum Disorder (NMOSD) is an autoimmune neurological disorder that is characterized by optic neuritis and longitudinally-extended transverse myelitis lesions in spinal segments. Magnetic Resonance Imaging (MRI) findings are part of the diagnostic process in NMOSD patients, and abnormal lesion patterns may cause deviation from a correct diagnosis. Clinical Presentation and Intervention: A 43-year-old female patient with abrupt cognitive loss, motor dysfunction and tumefactive spread of the demyelinating lesions in her brain presented to the Neurology Clinic of Kashani Hospital. Anti Aquaporine 4(AQP-4) antibody was observed, and the patient responded well to the NMOSD treatment. Conclusion: NMOSD can be considered a differential diagnosis during an episode of Fulminant Demyelinating Disorder (FDD) with the tumefactive spread of the lesions. }, URL = {http://cjns.gums.ac.ir/article-1-257-en.html}, eprint = {http://cjns.gums.ac.ir/article-1-257-en.pdf}, journal = {Caspian Journal of Neurological Sciences}, doi = {10.32598/CJNS.5.17.96}, year = {2019} }