:: Volume 3, Number 10 (Summer 2017) ::
Caspian.J.Neurol.Sci 2017, 3(10): 128-134 Back to browse issues page
Non-adherence to Disease-Modifying Treatments in Patients with Multiple Sclerosis
Seyed-Ali Roudbary, Shahrokh Yousefzadeh-Chabok, Hamid Behzadnia , Babak Bakhshayesh-Eghbali, Mohamadreza Emamhadi, Amirreza Ghayeghran, Hamidreza Hatamian, Alia Saberi, Sasan Andalib
Department of Neurosurgery, Poursina Hospital, School of Medicine, Guilan University of Medical Sciences, Rasht, IranFaculty of Medicine, Mashhad Branch, Islamic Azad University, Mashhad, Iran; neurosurgery95@gmail.com
Abstract:   (1343 Views)
Background: Multiple Sclerosis (MS) is a debilitating disease of the central nervous system. Usually, long-term MS medications are injected intramuscularly or subcutaneously, making them intolerable for many MS patients.
Objectives: In the present study, the rate and the causes of non-adherence to MS disease-modifying drugs (DMDs) were assessed in patients with MS.
Materials and Methods: Two hundred and three MS patients of Guilan MS Society were interviewed demographic and clinical data of the patients were collected.
Results: Among the 203 patients, 73.9% were female. The mean±SD age of the patients was 32.47±9.15. Non-adherence to DMDs was due to side effects (21.7%) and requests of the families (21.7%) or ineffectiveness (17.4%). Significant association was seen between the non-adherence to DMDs and gender (p=0.015) and relapses (p=0.021).
Conclusion: The evidence from the present study suggests that there is a high rate of non-adherence to DMDs in MS patients in Guilan.
Keywords: Multiple Sclerosis, Medication Adherence
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Type of Study: Research | Subject: Special

DOI: 10.18869/acadpub.cjns.3.10.128

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Volume 3, Number 10 (Summer 2017) Back to browse issues page