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:: Volume 2, Issue 5 (Spring 2016) ::
Caspian.J.Neurol.Sci 2016, 2(5): 36-41 Back to browse issues page
Doppler Microembolic Signals in Behcet's Disease with Nervous System Involvement
Zahra Mirfeizi , Ali Ghabeli-Juibary , Mohsen Moohebati , Mahmoudreza Azarpazhooh , Payam Sasannejad
Assistant Professor of Neurology, Department of Neurology, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran ; sasannejadp@mums.ac.ir
Abstract:   (1933 Views)

Background: Behçet’s disease (BD) is a multisystemic inflammatory vasculitis of unknown etiology, and vasculitis being its major pathological feature. Objectives: We studied the prevalence of microembolic signals (MES) in patients with diagnosis Behçet's disease. We also tried to determine the frequency of MES in BD patients with or without neurological involvement.

Materials and Methods: This study enrolled 40 patients who fulfilled the diagnostic criteria of International Study Group for BD during 2012 to 2013. Bilateral transcranialDoppler ultrasound of the middle cerebral arteries was performed by multigate method. MES were identified based on the criteria of International Consensus group on Microembolus Detection.

Results: We found MES in none of our patients with BD. We measured intima-media thickness in all patients.

Conclusion: It seems that in our population core histopathologic phenomenon to be other than MES andvasculiticphenomenonmay be implicated as a pathophysiologic factor for central nervous system involvement.The clarification of this subject needs further investigations on Iranian BD patients.

Keywords: Behçet’s Disease, Transcranial Doppler, Microembolic Signals
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Type of Study: Research | Subject: Special
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DOI: 10.18869/acadpub.cjns.2.5.36

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Mirfeizi Z, Ghabeli-Juibary A, Moohebati M, Azarpazhooh M, Sasannejad P. Doppler Microembolic Signals in Behcet's Disease with Nervous System Involvement. Caspian.J.Neurol.Sci. 2016; 2 (5) :36-41
URL: http://cjns.gums.ac.ir/article-1-95-en.html
Volume 2, Issue 5 (Spring 2016) Back to browse issues page
مجله علوم اعصاب کاسپین Caspian Journal of Neurological Sciences

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