دوره 3، شماره 4 - ( 7-1396 )                   جلد 3 شماره 4 صفحات 240-231 | برگشت به فهرست نسخه ها


XML Print


Download citation:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:

Etemadifar M, Fazli A. Myelin-Oligodendrocyte Glycoprotein Antibodies Spectrum Disorders. Caspian J Neurol Sci 2017; 3 (4) :231-240
URL: http://cjns.gums.ac.ir/article-1-206-fa.html
Myelin-Oligodendrocyte Glycoprotein Antibodies Spectrum Disorders. مجله علوم اعصاب کاسپین. 1396; 3 (4) :231-240

URL: http://cjns.gums.ac.ir/article-1-206-fa.html


چکیده:   (3301 مشاهده)
Myelin-Oligodendrocyte Glycoprotein (MOG) is an adhesive molecule responsible for myelin sheath structural integrity and maintenance. Patients with spectrum of inflammatory demyelinating disease particularly in central nervous system are reported to have antibodies against this protein. Diseases such as multiple sclerosis, clinically isolated syndrome, neuro-myelitis optica (NMO) spectrum disorders, acute disseminated encephalomyelitis, transverse myelitis and Optic neuritis seemed to have a correlation with anti-MOG antibodies. MRI findings of seropositive cases revealed spinal lesions, particularly in lower segments. For treatment of these patients methotrexate and azathioprine are suggested. Plasmaphresis and intravenous immunoglobulin may be useful too. However fingolimod and interferons can deteriorate the conditions. Finally it is concluded that anti-MOG antibodies can be a biomarker for CNS demyelinating disorders.
متن کامل [PDF 622 kb]   (1564 دریافت)    
نوع مطالعه: مروری | موضوع مقاله: تخصصي
دریافت: 1396/9/9 | پذیرش: 1396/9/9 | انتشار: 1396/9/9

ارسال نظر درباره این مقاله : نام کاربری یا پست الکترونیک شما:
CAPTCHA

بازنشر اطلاعات
Creative Commons License این مقاله تحت شرایط Creative Commons Attribution-NonCommercial 4.0 International License قابل بازنشر است.

کلیه حقوق این وب سایت متعلق به مجله علوم اعصاب کاسپین می باشد.

طراحی و برنامه نویسی : یکتاوب افزار شرق

© 2024 CC BY-NC 4.0 | Caspian Journal of Neurological Sciences

Designed & Developed by : Yektaweb