Volume 3, Issue 10 (Summer 2017)                   Caspian.J.Neurol.Sci 2017, 3(10): 128-134 | Back to browse issues page


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Roudbary S, Yousefzadeh-Chabok S, Behzadnia H, Bakhshayesh-Eghbali B, Emamhadi M, Ghayeghran A, et al . Non-adherence to Disease-Modifying Treatments in Patients with Multiple Sclerosis. Caspian.J.Neurol.Sci. 2017; 3 (10) :128-134
URL: http://cjns.gums.ac.ir/article-1-178-en.html
1- Neurology Department, Poursina Hospital, School of Medicine, Guilan University of Medical Sciences, Rasht, Iran
2- Neuroscience Research Center, Department of Neurosurgery, Poursina Hospital, School of Medicine, Guilan University of Medical Sciences, Rasht, Iran
3- Department of Neurosurgery, Poursina Hospital, School of Medicine, Guilan University of Medical Sciences, Rasht, IranFaculty of Medicine, Mashhad Branch, Islamic Azad University, Mashhad, Iran; neurosurgery95@gmail.com
4- Neuroscience Research Center, Department of Neurology, Poursina Hospital, School of Medicine, Guilan University of Medical Sciences, Rasht, Iran
5- Brachial Plexus and Peripheral Nerve Injury Center, Guilan University of Medical Science, Rasht, Iran
Abstract:   (2002 Views)
Background: Multiple Sclerosis (MS) is a debilitating disease of the central nervous system. Usually, long-term MS medications are injected intramuscularly or subcutaneously, making them intolerable for many MS patients.
Objectives: In the present study, the rate and the causes of non-adherence to MS disease-modifying drugs (DMDs) were assessed in patients with MS.
Materials and Methods: Two hundred and three MS patients of Guilan MS Society were interviewed demographic and clinical data of the patients were collected.
Results: Among the 203 patients, 73.9% were female. The mean±SD age of the patients was 32.47±9.15. Non-adherence to DMDs was due to side effects (21.7%) and requests of the families (21.7%) or ineffectiveness (17.4%). Significant association was seen between the non-adherence to DMDs and gender (p=0.015) and relapses (p=0.021).
Conclusion: The evidence from the present study suggests that there is a high rate of non-adherence to DMDs in MS patients in Guilan.
 
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Type of Study: Research | Subject: Special
Received: 2017/07/28 | Accepted: 2017/07/28 | Published: 2017/07/28

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