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:: Volume 3, Issue 10 (Summer 2017) ::
Caspian.J.Neurol.Sci 2017, 3(10): 128-134 Back to browse issues page
Non-adherence to Disease-Modifying Treatments in Patients with Multiple Sclerosis
Seyed-Ali Roudbary , Shahrokh Yousefzadeh-Chabok , Hamid Behzadnia , Babak Bakhshayesh-Eghbali , Mohamadreza Emamhadi , Amirreza Ghayeghran , Hamidreza Hatamian , Alia Saberi , Sasan Andalib
Department of Neurosurgery, Poursina Hospital, School of Medicine, Guilan University of Medical Sciences, Rasht, IranFaculty of Medicine, Mashhad Branch, Islamic Azad University, Mashhad, Iran; neurosurgery95@gmail.com
Abstract:   (1487 Views)
Background: Multiple Sclerosis (MS) is a debilitating disease of the central nervous system. Usually, long-term MS medications are injected intramuscularly or subcutaneously, making them intolerable for many MS patients.
Objectives: In the present study, the rate and the causes of non-adherence to MS disease-modifying drugs (DMDs) were assessed in patients with MS.
Materials and Methods: Two hundred and three MS patients of Guilan MS Society were interviewed demographic and clinical data of the patients were collected.
Results: Among the 203 patients, 73.9% were female. The mean±SD age of the patients was 32.47±9.15. Non-adherence to DMDs was due to side effects (21.7%) and requests of the families (21.7%) or ineffectiveness (17.4%). Significant association was seen between the non-adherence to DMDs and gender (p=0.015) and relapses (p=0.021).
Conclusion: The evidence from the present study suggests that there is a high rate of non-adherence to DMDs in MS patients in Guilan.
Keywords: Multiple Sclerosis, Medication Adherence
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Type of Study: Research | Subject: Special
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DOI: 10.18869/acadpub.cjns.3.10.128

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Roudbary S, Yousefzadeh-Chabok S, Behzadnia H, Bakhshayesh-Eghbali B, Emamhadi M, Ghayeghran A, et al . Non-adherence to Disease-Modifying Treatments in Patients with Multiple Sclerosis. Caspian.J.Neurol.Sci. 2017; 3 (10) :128-134
URL: http://cjns.gums.ac.ir/article-1-178-en.html
Volume 3, Issue 10 (Summer 2017) Back to browse issues page
مجله علوم اعصاب کاسپین Caspian Journal of Neurological Sciences

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